Ostarine Gynecomastia Problem: Causes and Reversal

Ostarine is a popular go-to ‘safe steroid’ for bodybuilders looking to grow muscles. But along with growing muscles, some bodybuilders or Ostarine users claim to have experience Gyno. 

So, you might wonder if Ostarine Gyno is actually a thing or not?

No, Ostarine Gyno is not a thing. It is not known to cause Gyno among the users. Ostarine is a SARM that is formulated to mimic high binding affinity without the side effects. However, not all body reacts the same. Some users have reported having gyno while they were taking Ostarine.

Gyno is the formulation of fat tissue in male users. And there are more to Gyno and SARMs. 

In this article, I will explain about Ostarine causing Gyno and how to reverse it from Gyno. 

Let’s proceed.

Ostarine: How It Works

Ostarine is s new class of anabolic substances known as SARMS (selective androgen receptor modulators). SARMs were created with the goal of outdoing exogenous testosterone as a treatment (anabolic steroids).

It emulates the muscle-building properties of anabolic steroids without having as many negative effects. Scientists aimed to create SARMs for fitness with a high binding affinity towards androgen receptors and tissue selectivity.

Ostarine aims to lower the adverse effect of anabolic steroids on cardiovascular, androgenic, and estrogenic health. It uses the tissue selectivity of its mechanism. 

However, it is still unclear how SARMs’ tissue selectivity is activated transcriptionally. So, there is a possibility that SARMs can have negative side effects like anabolic steroids.

SARMs are only to be used as “research compounds” up till more human trials are carried out.

SARMs are viewed as a “safe version of steroids” and are therefore very well-liked by the bodybuilding world. 

However, this claim is still doubtful and is yet to be proved right. It is based on current research and a substantial amount of anecdotal information from our doctors. And users have reported cases of Gyno. 

The next segment will be on Gyno and how it happens in men. 

Ostarine Gynecomastia Problem

Can Ostarine Cause Gyno?

When Ostarine is taken, no conversion to estrogen and DHT can occur. Because SARMs inhibit aromatase and 5-alpha reductase enzyme activity.

Therefore, theoretically, Ostarine using bodybuilders can gain lean muscles would. And they would gain muscle without the negative side effects like hair loss and Gynocomastia.

Yet, bodybuilders on Ostarine have been reporting cases of gyno and male pattern baldness in real-life scenario. 

The side effects occur is because the androgen receptor (AR) binds to the natural testosterone of a person. But, SARMs take part with the natural testosterone for binding with AR, thus interrupting a natural procedure.

Ostarine has a remarkably higher binding affinity as opposed to natural testosterone and hench wins the contest. As a result, more testosterone is left free to convert to estrogen and DHT.

Thus, because of the testosterone left to convert to estrogen, SARMs secondarily increase estrogen and DHT levels.  

What Is Gyno: How It Happens from SARMs

SARMs like Ostarine flood the human body with androgen receptors that bind tightly to testosterone.

Now there are fewer open androgen receptors as SARM dosage increases. So, more of your available testosterone will be directed toward estrogen and DHT conversion.

So when more testosterone is directed towards the estrogen, esSARtrogen level in the male user rises. 

Increased level of estrogen causes the fatty tissues around the nipple to grow. Breast size increases. And this condition is called Gyno, short for Gynecomastia.

One puts themselves in danger of various side effects brought on by excessive amounts of estrogen. Including gynecomastia, when this scenario plays out and Estrogen climbs to out-of-range levels (gyno).

Additionally, SARMs reduce testosterone in a dose-dependent manner.

Gyno can also result from low amounts of testosterone in the body. Or a hormonal imbalance in which the ratio of testosterone to estrogen is abnormally low.

Prior History of Gyno

Users with a previous history of Gyno are more susceptible to having possible Gyno from Ostarine.

For example, males who have had a gyno during their puberty. Or, males who have more fatty tissue in general. They may see the symptoms of Gyno more than users without a prior history. 

It’s that their body is more prone to the effects of Ostarine than other

How to Detect Gyno

Because the rumor of Ostarine Gyno is so prevalent, sometimes that has a psychological effect on users.

You may see yourself in the mirror differently, thinking you have Gyno. And it is understandably an uncomfortable state to be in. So why not be completely sure of it? 

There are some ways you can be sure if you have Gyno or not – 

  • Feel the area around your nipple with your hand. If you notice a firm small size of lump around it, that may be Gyno. However, there are also firm cells that are glands, so be aware of that.
  • Have your blood tested for Gynecomastia.
  • Request for a mammogram. It is a small-dose X-ray of your breasts.

Can Ostarine Gyno Be Reversed?

Gynecomastia cases typically go away on their own over time. If you notice that taking Ostarine is causing Gyno, stop taking Ostarine. The Gyno issue will be reversed on its own. 

You can also have testosterone in a cycle for making up for the lack of testosterone. 

However, that is for the early cases of Gyno. If it grows over time, Gyno will take a longer time to go.

Gynecomastia may require treatment if an underlying illness like hypogonadism, starvation, or cirrhosis is what’s to blame. 


Some users with gynecomastia can see positive results from taking medications for disorders like Gynocomstia and other illnesses. They consist of:

  • Tamoxifen (Soltamox)
  • anti-aromatase drugs like anastrozole (Arimidex)

The FDA has approved the above drugs. But, they have not been completely approved for prescribing the patients with gynecomastia.

There are some medications for bodybuilders to reverse or prevent Ostarine Gyno.

Bodybuilders may use the weak aromatase inhibitor arimistane (Androsta-3,5-diene-7,17-dione). Taking these drugs while being on SARMs could prevent gynecomastia and other estrogenic side effects. There are alternatives as well.

While letrozole, anastrozole, and other AIs are frequently used during steroid cycles. They’re probably too powerful for SARMs, leading to an estrogen deficit (as opposed to preventing excessive levels).

For better suitability for your body, you can compare Arimidex with nolvadex for the steroid cycle. 

You can also try these supplements to raise the production of testosterone amount in your body.

MALE FORCEThis supplement helps the body to produce Testosterone and HGH naturally and ensures the aging decline.
TESTO 911This supplement has all-natural ingredients to improve testosterone production.


Your doctor might suggest surgery if the size of your breasts persists despite initial treatment or observation.

Two procedures for gynecomastia are –

  • Liposuction. The breast gland tissue is not removed with this procedure; only the breast fat is.
  • Mastectomy. The breast gland tissue is removed during this kind of surgery. The procedure is frequently performed with very few incisions. Less recuperation time is required following this less invasive kind of surgery.

Ostarine Dosage

Now, that was all about Ostarine Gyno’s problems, causes, and reversal. 

If you take Ostarin in the proper dosage, the probability of you to have Gyno will be very small. 

You can safely take your Ostarine dose once per day. Because the half-life of this SARM is near about 24 hours. Remember that your blood levels of the chemical will stay at their peak for the whole period.

Depending on the dose, some users may decide to divide the dose into two daily administrations. They take half in the morning and the other half in the evening.

Ostarine is an oral SARM, therefore there are no injections needed, making it simple to consume.

Patients with diseases that cause muscle wasting, can gain more muscle mass even with 1mg of Ostarine.

For builders starting to grow muscles, this is a great dosage to start with. The side effects at this dosage are little to none. 


What are the side effects of Ostarine?

More than half of SARM users reported side effects such as depression, shrinking testicles, and acne. More than 90% of males said they were happy with SARMs. They had gained muscle mass. Despite having apparent beneficial effects, more than 50% of SARM users report severe negative effects.

Can you bulk on Ostarine?

Ostarine can compete with numerous steroids. Even though it’s not one of the strongest bulking SARMs. If you want this SARM to work well for you, add it to a stack. It is a more efficient way than using it alone. Consider your use of Ostarine carefully if you are an athlete in competition.

Does Ostarine cause hair loss?

No study suggests that SARMs induce hair loss. Molecular biology studies suggest some SARMs, like Ostarine (MK2866) and S4 Andarine, may actually stop hair loss. And it was studied for low to moderate dosages. Although it has yet to be measured in a controlled clinical study environment.


That concludes everything about Ostarine Gyno and ways to reverse it. 

As common as the myth is around SARMs nowadays, the side effects are minimal.

If you are looking to boost your anabolic state, Ostarine AKA MK-2866 is one of the best options out there. 

Best of luck with your bodybuilding journey!

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